What was Antoine-Laurent Lavoisier's most important contribution to chemistry in 1789?

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1. In 1789 Antoine-Laurent Lavoisier published Traité élémentaire de chimie (Elements of Chemistry) where he established quantitative chemistry by careful measurements.

2. From experiments on combustion and other chemical reactions in closed systems he showed that the total mass before and after a chemical change is the same, i.e. $m_{reactants}=m_{products}$. This is the Law of Conservation of Mass.

3. The other laws listed were established later or by others: the Law of Definite Proportions (Proust), the Law of Multiple Proportions (Dalton), and the Law of Conservation of Energy belongs to thermodynamics and was formulated later.

Therefore the correct choice is the Law of Conservation of Mass.

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