Select the most appropriate antonym of the given word: Affirmative.

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The word 'affirmative' means expressing agreement, approval, or consent. Its antonym would be a word that expresses denial, disagreement, or refusal. Among the options, 'Negative' is the direct opposite of 'Affirmative'. 'Sanction', 'Acquiescence', and 'Accession' all imply agreement or approval in some form, so they are not antonyms.

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